Vertigo Research Today is a free monthly online journal that collates and summarizes the latest research about Vertigo, including details on causes, symptoms, treatment, dizziness.

Vogt-Koyanagi-Harada syndrome in a Greenlandic Inuit.

Ostergaard J, Goldschmidt E, Andersen N

Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Purpose: To report a case of Vogt-Koyanagi-Harada syndrome (VKH) in an Inuit. Methods: We carried out a medical evaluation and human leucocyte antigen (HLA) genotyping. Results: A 36-year-old male Inuit developed severely decreased vision, intense headache and vertigo over a 3-week period. Ocular examination revealed panuveitis with bilateral serous retinal detachment and optic nerve head oedema. There was no history of ocular trauma or evidence suggestive of other disease entities. The patient responded well to high-dose systemic prednisolone. Vitiligo presented late in the course. Conclusions: This case report describes the first published case of VKH in a patient of Inuit ancestry. The patient was homozygous for HLA-DR4, a genotype previously associated with VKH.

Published 27 November 2007 in Acta Ophthalmol Scand.
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